@UC Berkeley
Selected Publications
Aster proteins regulate the accessible cholesterol pool in the plasma membrane
Ferrari A*, He C*, Kennelly JP, Sandhu J, Xiao X, Chi X, Jiang H, Young SG, and Tontonoz P
*equal contribution
Molecular and Cellular Biology, 2020
PMCID: PMC7491948
Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake
Ferrari A*, Whang E*, Xiao X, Kennelly JP, Romartinez-Alonso B, Mack JJ, Weston T, Chen K, Kim Y, Tol MJ, Bideyan L, Nguyen A, Gao Y, Cui L, Bedard AH, Sandhu J, Lee SD, Fairall L, Williams KJ, Song W, Munguia P, Russell RA, Martin MG, Jung ME, Jiang H, Schwabe JWR, Young SG, Tontonoz P
*equal contribution
Science, 2023
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PMCID: PMC11073449
Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health
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Lockhart SM*, Muso M*, Zvetkova I, Lam BYH, Ferrari A, Schoenmakers E, Duckett K, Leslie J, Collins A, Romartínez-Alonso B, Tadross JA, Jia R, Gardner EJ, Kentistou K, Zhao Y, Day F, Mörseburg A, Rainbow K, Rimmington D, Mastantuoni M, Harrison J, Nus M, Guma’a K, Sherratt-Mayhew S, Jiang X, Smith KR, Paul DS, Jenkins B, Koulman A, Pietzner M, Langenberg C, Wareham N, Yeo GS, Chatterjee K, Schwabe J, Oakley F, Mann DA, Tontonoz P, Coll AP, Ong K, Perry JRB, O’Rahilly S
*equal contribution
Nature Metabolism, 2024
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PMCID: PMC11496107
T cell cholesterol transport is a metabolic checkpoint that links intestinal immune responses to dietary lipid absorption
Gao Y*, Kennelly JP*, Xiao X, Whang E, Ferrari A, Bedard AH, Mack JJ, Nguyen AH, Weston T, Uchiyama LF, Lee MS, Young SG, Bensinger SJ, Tontonoz P
*equal contribution
bioRxiv, 2024.03.08.584164
PMCID: PMC10979874
Cholesterol binding to VCAM-1 promotes vascular inflammation
Kennelly JP*, Xiao X*, Gao Y, Kim S, Hong SG, Villanueva M, Ferrari A, Vanharanta L, Nguyen A, Nagari RT, Burton NR, Tol MJ, Becker AP, Lee MJ, Ikonen E, Backus KM, Mack JJ, Tontonoz P
*equal contribution
bioRxiv, 2024.09.17.613543
Dietary control of peripheral adipose storage capacity through membrane lipid remodeling
Tol MJ*, Shimanaka Y*, Bedard AH, Sapia J, Cui L, Colaço-Gaspar M, Hofer P, Ferrari A, Qian K, Kennelly JP, Lee SD, Gao Y, Xiao X, Gao J, Mack JJ, Weston TA, Pan C, Lusis AJ, Williams KJ, Su B, Pike DP, Reed A, Milosevich N, Cravatt BF, Arita M, Young SG, Ford DA, Zechner R, Vanni S, Tontonoz P
*equal contribution
bioRxiv, 2024.10.25.620374
Hepatic nonvesicular cholesterol transport is critical for systemic lipid homeostasis​
Xiao X*, Kennelly JP*, Ferrari A, Clifford BL, Whang E, Gao Y, Qian K, Sandhu J, Jarrett KE, Brearley-Sholto MC, Nguyen A, Nagari RT, Lee MS, Zhang S, Weston TA, Young SG, Bensinger SJ, Villanueva CJ, de Aguiar Vallim TQ, Tontonoz P
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*equal contribution
Nature Metabolism, 2023
PMCID: PMC9995220
NanoSIMS imaging of lipid absorption by intestinal enterocytes
Chen K, Song W, Russell R, Ferrari A, Darwish T, Tontonoz P, Young SG, Jiang H
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Journal of Lipid Research, 2022
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PMCID: PMC9672438
Interferon-mediated reprogramming of membrane cholesterol to evade bacterial toxins
Zhou QD, Chi X, Lee MS, Hsieh WY, Mkrtchyan JJ, Feng A-C, He C, York AG, Bui VL, Kronenberger EB, Ferrari A, Xiao X, Daly AE, Tarling EJ, Damoiseaux R, Scumpia PO, Smale ST, Williams KJ, Tontonoz P, and Bensinger SJ
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Nature Immunology, 2020
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PMCID: PMC6469685
Sandhu J, Li S, Fairall L, Pfisterer SG, Gurnett JE, Xiao X, Weston TA, Vashi D, Ferrari A, Orozco JL, Hartman CL, Strugatsky D, Lee SD, He C, Hong C, Jiang H, Bentolila LA, Gatta AT, Levine TP, Ferng A, Lee R, Ford DA, Young SG, Ikonen E, Schwabe JWR, and Tontonoz P
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Cell, 2018
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PMCID: PMC6469685
​HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning
Ferrari A, Longo R, Fiorino E, Silva R, Mitro N, Cermenati G, Gilardi F, Desvergne B, Andolfo A, Magagnotti C, Caruso D, Fabiani ED, Hiebert SW, and Crestani M
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Nature Communications, 2017
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PMCID: PMC5522415
Galmozzi A*, Mitro N*, Ferrari A, Gers E, Gilardi F, Godio C, Cermenati G, Gualerzi A, Donetti E, Rotili D, Valente S, Guerrini U, Caruso D, Mai A, Saez E, De Fabiani E, Crestani M
*equal contribution
Diabetes, 2013
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PMCID: PMC3581211